DMSO (Dimethyl Sulfoxide): Therapeutic Overview

$200.00

Therapeutic Uses (with evidence):

Method of Administration

  • Primary Route: Intravenous (IV) infusion
    This method provides high systemic absorption and rapid onset of action, allowing the compound to act quickly at the cellular level.

  • Alternative Route: Oral administration
    (Less effective compared to IV delivery.)

1. Interstitial Cystitis (IC):

  • FDA-approved for intravesical (bladder) use in treating IC (chronic bladder pain).

  • Helps reduce inflammation and pain.

2. Pain and Inflammation:

  • Used topically for muscle and joint pain, arthritis, sprains.

  • Acts by:

    • Reducing inflammatory cytokines

    • Blocking pain nerve conduction

  • 3. Scleroderma and Other Autoimmune Disorders:

  • Applied topically to reduce skin hardening, inflammation, and pain.

4. Wound and Burn Healing:

  • May promote tissue repair and reduce pain and inflammation in minor wounds and burns.

5. Cryopreservation:

  • Widely used in biological and medical labs to protect cells and tissues during freezing.

Experimental or Off-Label Uses (with limited or mixed evidence):

  • Traumatic brain injury and spinal cord injury (neuroprotective potential)

  • Cancer (as a solvent in experimental therapies; not directly cytotoxic)

  • Herpes simplex infections

  • Rheumatoid arthritis

  • Headaches and migraines

  • Shingles

Safety, Side Effects, and Risks:

Common Side Effects:

  • Garlic-like body odor or breath

  • Skin irritation at the application site

  • Headache, dizziness, nausea (especially at higher doses)

Serious (but rare):

  • Eye damage with long-term exposure

  • Possible toxic interactions if used with certain drugs (as it enhances absorption)

  • Sterility or contamination risks when not pharmaceutical grade

Important Notes:

  • Only one DMSO formulation is FDA-approved (for bladder instillation).

  • Topical and oral DMSO use in humans remains controversial and often unregulated.

  • Veterinary use is more common, especially in treating joint injuries in horses.